Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Adenomatous polyposis coli alteration in digestive endocrine tumours: correlation with nuclear translocation of beta-catenin and chromosomal instability.

Endocrine-related cancer - 1 Dec 2008

Pizzi Silvia, Azzoni Cinzia, Tamburini Elisa, Bottarelli Lorena, Campanini Nicoletta, D'Adda Tiziana, Fellegara Giovanni, Luong Tu Vinh, Pasquali Claudio, Rossi Giulio, Delle Fave Gianfranco, Camisa Roberta, Bordi Cesare, Rindi Guido

Abstract excerpt

The role of Wnt pathway in digestive endocrine tumours is debated. The aim of this work is to investigate key players in Wnt pathway by a multimodal approach. Sixty cases (49 well-differentiated and 11 poorly differentiated) were investigated for methylation of adenomatous polyposis coli (APC) an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli Protein
Share to beta Catenin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomal Instability

Share to Endocrine Gland Neoplasms

Share to Gastrointestinal Neoplasms

Share to Immunoenzyme Techniques

Share to Loss of Heterozygosity

Share to Wnt Proteins

Source

Identifiers

PMID: 18632876
DOI: 10.1677/ERC-07-0230

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18632876-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adenomatous polyposis coli alteration in digestive endocrine tumours: correlation with nuclear translocation of beta-catenin and chromosomal instability.PMID 18632876Read ↗

Endocrine tumours of the gastrointestinal tract: aetiology, molecular pathogenesis and genetics.Semantic proximity Read ↗

The role of the adenomatous polyposis coli (APC) in oral squamous cell carcinoma.Semantic proximity Read ↗

Analysis of molecular pathways in sporadic neuroendocrine tumors of the gastro‐entero‐pancreatic systemSemantic proximity Read ↗

Wnt-Independent and Wnt-Dependent Effects of APC Loss on the Chemotherapeutic ResponseSemantic proximity Read ↗

The adenomatous polyposis coli (APC) tumour suppressor--genetics, function and disease.Semantic proximity Read ↗

Expression and mutation pattern of β-catenin and adenomatous polyposis coli in colorectal cancer patients.Semantic proximity Read ↗

Wnt/Beta-Catenin/Tcf Signaling: A Critical Pathway in Gastrointestinal TumorigenesisSemantic proximity Read ↗

Colorectal cancer and genetic alterations in the Wnt pathway.Semantic proximity Read ↗

Abnormalities of the APC/beta-catenin pathway in endometrial cancer.Semantic proximity Read ↗

Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia.Semantic proximity Read ↗

Hypermethylation of APC promoter 1A is associated with moderate activation of Wnt signalling pathway in a subset of colorectal serrated adenomas.Semantic proximity Read ↗

Adenomatous polyposis coli/beta-catenin interaction and downstream targets: altered gene expression in gastrointestinal tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.