Article
Haplotypic analysis of the MMP-9 gene in relation to coronary artery disease.
Journal of molecular medicine (Berlin, Germany) - 1 May 2003
Morgan Angharad R, Zhang Baiping, Tapper William, Collins Andrew, Ye Shu
Abstract excerpt
Matrix metalloproteinase-9 (MMP-9) plays an important role in the pathogenesis of atherosclerosis, the pathology underlying the majority of coronary artery disease. We previously identified several polymorphisms in the gene encoding MMP-9. In this study we tested the hypothesis that variation in the matrix metalloproteinase-9 gene influences the development of atherosclerosis. Three common polymorphisms, i.e....
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