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Article

Analysis of the complete open reading frame of genotype 2b hepatitis C virus in association with the response to peginterferon and ribavirin therapy.

PloS one - 1 Jan 2011

Kadokura Makoto, Maekawa Shinya, Sueki Ryota, Miura Mika, Komase Kazuki, Shindo Hiroko, Amemiya Fumitake, Uetake Tomoyoshi, Inoue Taisuke, Sakamoto Minoru, Nakagawa Mina, Sakamoto Naoya, Watanabe Mamoru, Enomoto Nobuyuki

Abstract excerpt

BACKGROUND AND AIMS: Patients infected with genotype 2b hepatitis C virus (HCV) generally can achieve favorable responses to pegylated-interferon plus ribavirin therapy (PEG-IFN/RBV). However, a proportion of patients show poorer responses and the correlation between viral sequence variation and treatment outcome remains unclear. METHODS: The pretreatment complete open reading frame (ORF) sequences of genotype 2b...

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Identifiers

PMID: 21935415
DOI: 10.1371/journal.pone.0024514
PMCID: PMC3174186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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