Article
West Nile virus genetic diversity is maintained during transmission by Culex pipiens quinquefasciatus mosquitoes.
PloS one - 1 Jan 2011
Brackney Doug E, Pesko Kendra N, Brown Ivy K, Deardorff Eleanor R, Kawatachi Jon, Ebel Gregory D
Abstract excerpt
Due to error-prone replication, RNA viruses exist within hosts as a heterogeneous population of non-identical, but related viral variants. These populations may undergo bottlenecks during transmission that stochastically reduce variability leading to fitness declines. Such bottlenecks have been documented for several single-host RNA viruses, but their role in the population biology of obligate two-host viruses...
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