Article
Vector-borne transmission imposes a severe bottleneck on an RNA virus population.
PLoS pathogens - 1 Sept 2012
Forrester Naomi L, Guerbois Mathilde, Seymour Robert L, Spratt Heidi, Weaver Scott C
Abstract excerpt
RNA viruses typically occur in genetically diverse populations due to their error-prone genome replication. Genetic diversity is thought to be important in allowing RNA viruses to explore sequence space, facilitating adaptation to changing environments and hosts. Some arboviruses that infect both a mosquito vector and a mammalian host are known to experience population bottlenecks in their vectors, which may...
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