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Article

Transmission bottlenecks and RNAi collectively influence tick-borne flavivirus evolution

1 Jul 2016

Abstract excerpt

Arthropod-borne RNA viruses exist within hosts as heterogeneous populations of viral variants and, as a result, possess great genetic plasticity. Understanding the micro-evolutionary forces shaping these viruses can provide insights into how they emerge, adapt, and persist in new and changing ecological niches. While considerable attention has been directed toward studying the population dynamics of...

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PMID: 28058113
DOI: 10.1093/ve/vew033

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