Article
Isolation of a new cell population in the glioblastoma microenvironment.
Journal of neuro-oncology - 1 Feb 2012
Clavreul Anne, Etcheverry Amandine, Chassevent Agnès, Quillien Véronique, Avril Tony, Jourdan Marie-Lise, Michalak Sophie, François Patrick, Carré Jean-Luc, Mosser Jean, Menei Philippe
Abstract excerpt
Glioblastoma (GB) is a highly infiltrative tumor recurring in 90% of cases within a few centimeters of the resection cavity, even in cases of complete tumor resection and adjuvant chemo/radiotherapy. This observation highlights the importance of understanding this special zone of brain tissue surrounding the tumor. It is becoming clear that the nonneoplastic stromal compartment of most solid cancers plays an...
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