Article
Glioblastoma-associated stromal cells (GASCs) from histologically normal surgical margins have a myofibroblast phenotype and angiogenic properties.
The Journal of pathology - 1 May 2014
Clavreul Anne, Guette Catherine, Faguer Rogatien, Tétaud Clément, Boissard Alice, Lemaire Laurent, Rousseau Audrey, Avril Tony, Henry Cécile, Coqueret Olivier, Menei Philippe
Abstract excerpt
Glioblastoma (GB) displays diffusely infiltrative growth patterns. Dispersive cells escape surgical resection and contribute to tumour recurrence within a few centimeters of the resection cavity in 90% of cases. We know that the non-neoplastic stromal compartment, in addition to infiltrative tumour cells, plays an active role in tumour recurrence. We isolated a new stromal cell population from the histologically...
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