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Article

Trisomic and allelic differences influence phenotypic variability during development of Down syndrome mice.

Genetics - 1 Dec 2011

Deitz Samantha L, Roper Randall J

Abstract excerpt

Individuals with full or partial Trisomy 21 (Ts21) present with clinical features collectively referred to as Down syndrome (DS), although DS phenotypes vary in incidence and severity between individuals. Differing genetic and phenotypic content in individuals with DS as well as mouse models of DS facilitate the understanding of the correlation between specific genes and phenotypes associated with Ts21. The...

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Identifiers

PMID: 21926299
DOI: 10.1534/genetics.111.131391
PMCID: PMC3241431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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