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Article

Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome.

American journal of medical genetics - 1 Feb 2002

Richtsmeier Joan T, Zumwalt Ann, Carlson Elaine J, Epstein Charles J, Reeves Roger H

Abstract excerpt

Trisomy for chromosome 21 (Chr 21) has profound effects on development that result in a constellation of phenotypes known as Down syndrome (DS). Distinctive craniofacial manifestations are among the few features common to all individuals with DS. The characteristic face of a person with DS result...

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Identifiers

PMID: 11840489
DOI: 10.1002/ajmg.10175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11840489-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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