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Article

The 341C/T polymorphism in the GSTP1 gene is associated with increased risk of oesophageal cancer.

BMC genetics - 11 Jun 2010

Li Dongping, Dandara Collet, Parker M Iqbal

Abstract excerpt

BACKGROUND: The Glutathione S-transferases (GSTs) comprise a group of enzymes that are critical in the detoxification of carcinogens. In this study the effects of polymorphisms in these genes on the risk of developing oesophageal squamous cell carcinoma (OSCC) were evaluated in a hospital-based c...

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Source

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Identifiers

PMID: 20540773
DOI: 10.1186/1471-2156-11-47
PMCID: PMC2891604

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20540773-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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The 341C/T polymorphism in the GSTP1 gene is associated with increased risk of oesophageal cancer.PMID 20540773Read ↗

GSTP1 c.341C>T gene polymorphism increases the risk of oral squamous cell carcinoma.Semantic proximity Read ↗

The glutathione S-transferase P1 341C>T polymorphism and cancer risk: a meta-analysis of 28 case-control studies.Semantic proximity Read ↗

Association of a deletion of GSTT2B with an altered risk of oesophageal squamous cell carcinoma in a South African population: a case-control study.Semantic proximity Read ↗

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Population-specific genetic associations with oesophageal squamous cell carcinoma in South Africa.Semantic proximity Read ↗

Polymorphisms of GSTT1 and related genes in head and neck cancer risk.Semantic proximity Read ↗

Polymorphisms of the glutathione S-transferase P1 gene and head and neck cancer susceptibility.Semantic proximity Read ↗

Glutathione S-transferase GSTM1, GSTM3, GSTP1 and GSTT1 genotypes and the risk of smoking-related oral and pharyngeal cancers.Semantic proximity Read ↗

The glutathione S-transferase GSTP1 polymorphism: effects on susceptibility to oral/pharyngeal and laryngeal carcinomas.Semantic proximity Read ↗

GSTM1, GSTT1, and the risk of squamous cell carcinoma of the head and neck: a mini-HuGE review.Semantic proximity Read ↗

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