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Article

CYP3A5 genotypes and risk of oesophageal cancer in two South African populations.

Cancer letters - 28 Jul 2005

Dandara Collet, Ballo Robea, Parker M Iqbal

Abstract excerpt

CYP3A5 is the major cytochrome P450 enzyme in the oesophagus and metabolises many potentially carcinogenic compounds. The frequencies of CYP3A5 allelic variants, CYP3A5*2, *3, *6 and *7 which code for enzymes with severely decreased activities were compared between 241 oesophageal cancer patients and 272 controls in Black and Mixed Ancestry South Africans. A significantly higher frequency of CYP3A5*3 was observed...

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Source

Identifiers

PMID: 15978331
DOI: 10.1016/j.canlet.2004.11.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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