Article
Genetic suppressor screens in haploids.
Methods in cell biology - 1 Jan 2011
Bai Xiaoying, Yang Zhongan, Jiang Hong, Lin Shuo, Zon Leonard I
Abstract excerpt
As a vertebrate genetic model, the zebrafish has been well recognized for its strength in studying a variety of biological processes and human diseases. Traditional forward genetic screens in zebrafish have generated a large pool of mutants with interesting phenotypes resembling human diseases but the underlying mechanisms are not well understood. A powerful approach to elucidate the mechanisms of these mutants...
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