Article
NOS1 ex1f-VNTR polymorphism affects prefrontal oxygenation during response inhibition tasks.
Human brain mapping - 1 Nov 2012
Kopf Juliane, Schecklmann Martin, Hahn Tim, Dieler Alica C, Herrmann Martin J, Fallgatter Andreas J, Reif Andreas
Abstract excerpt
Impulsivity is a trait shared by many psychiatric disorders and therefore a suitable intermediate phenotype for their underlying biological mechanisms. One of the molecular determinants involved is the NOS1 ex1f-VNTR, whose short variants are associated with a variety of impulsive behaviors. Fifty-six healthy controls were stratified into homozygous long (LL) (30 probands) and short (SS) (26 probands) allele...
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