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Article

A functional NOS1 promoter polymorphism interacts with adverse environment on functional and dysfunctional impulsivity.

Psychopharmacology - 1 Mar 2011

Reif Andreas, Kiive Evelyn, Kurrikoff Triin, Paaver Marika, Herterich Sabine, Konstabel Kenn, Tulviste Tiia, Lesch Klaus-Peter, Harro Jaanus

Abstract excerpt

RATIONALE: Neuronal nitric oxide synthase (NOS1) knockout results in increased impulsive aggression in mice under adverse housing conditions. In line with this, we have previously shown that a functional promoter polymorphism of NOS1, termed NOS1 ex1f-VNTR, is associated with impulsivity-related traits and related disorders. OBJECTIVE: This study aims to examine whether adverse environment interacts with the risk...

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Source

Identifiers

PMID: 20589495
DOI: 10.1007/s00213-010-1915-7

Genes

NOS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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