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Article

Influence of functional variant of neuronal nitric oxide synthase on impulsive behaviors in humans.

Archives of general psychiatry - 1 Jan 2009

Reif Andreas, Jacob Christian P, Rujescu Dan, Herterich Sabine, Lang Sebastian, Gutknecht Lise, Baehne Christina G, Strobel Alexander, Freitag Christine M, Giegling Ina, Romanos Marcel, Hartmann Annette, Rösler Michael, Renner Tobias J, Fallgatter Andreas J, Retz Wolfgang, Ehlis Ann-Christine, Lesch Klaus-Peter

Abstract excerpt

CONTEXT: Human personality is characterized by substantial heritability but few functional gene variants have been identified. Although rodent data suggest that the neuronal isoform of nitric oxide synthase (NOS-I) modifies diverse behaviors including aggression, this has not been translated to human studies. OBJECTIVES: To investigate the functionality of an NOS1 promoter repeat length variation (NOS1 Ex1f...

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Source

Identifiers

PMID: 19124687
DOI: 10.1001/archgenpsychiatry.2008.510

Genes

NOS1
GRIN1
RGS4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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