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Article

The effect of a functional NOS1 promoter polymorphism on impulsivity is moderated by platelet MAO activity.

Psychopharmacology - 1 Apr 2010

Laas Kariina, Reif Andreas, Herterich Sabine, Eensoo Diva, Lesch Klaus-Peter, Harro Jaanus

Abstract excerpt

RATIONALE: Platelet monoamine oxidase (MAO) activity is associated with impulsivity in clinical samples. Recently, a functional promoter polymorphism of neuronal nitric oxide synthase (NOS1) termed NOS1 ex1f-VNTR was found to have an effect on impulsivity-related traits and resulting psychopathology. OBJECTIVE: The study aims to explore the effect of both platelet MAO activity and NOS1 ex1f-VNTR genotype on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Impulsive Behavior

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Share to Nitric Oxide Synthase Type I

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 20186396
DOI: 10.1007/s00213-010-1793-z

Genes

NOS1

Provenance

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