Article
BRCA1 and BRCA2 germline mutations in 85 Iranian breast cancer patients.
Familial cancer - 1 Mar 2012
Keshavarzi Fatemeh, Javadi Gholam Reza, Zeinali Sirous
Abstract excerpt
Breast cancer is the most common cancer in Iranian women (Mousavi et al in Asian Pac J Cancer Prev 9(2):275-278, 2008). Genetic predisposition accounts for 15% of all breast cancers and germline mutations in breast cancer susceptibility genes, BRCA1 and BRCA2 are responsible for a substantial proportion of high-risk breast and breast/ovarian cancer families (Collaborative Group on Hormonal Factors in Breast...
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