Article
Germline BRCA1/BRCA2 mutations among high risk breast cancer patients in Jordan.
BMC cancer - 6 Feb 2018
Abdel-Razeq Hikmat, Al-Omari Amal, Zahran Farah, Arun Banu
Abstract excerpt
BACKGROUND: Breast cancer is the most common malignancy and the leading cause of cancer-related deaths among Jordanian women. With a median age of 50 years at diagnosis, a higher prevalence of hereditary breast cancer may be expected. The objective of this pilot study is to evaluate, for the first time, the contribution of germline mutations in BRCA1/2 to breast cancer among Jordanian patients. METHODS: Jordanian...
Topics
- Adult
- Aged
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Female
- Genetic Predisposition to Disease
- Germ-Line Mutation
- Humans
- Incidence
- Jordan
- Logistic Models