In vitro and in vivo activities of T4 endonuclease V mutants altered in the C-terminal aromatic region.

doi:10.1021/bi00468a002

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

In vitro and in vivo activities of T4 endonuclease V mutants altered in the C-terminal aromatic region.

Biochemistry - 24 Apr 1990

Ishida M, Kanamori Y, Hori N, Inaoka T, Ohtsuka E

Abstract excerpt

Genes encoding mutants of the thymine photodimer repair enzyme from bacteriophage T4 (T4 endonuclease V) having an amino acid substitution (T127M, W128A, W128S, Y129A, K130L, Y131A, Y132A) were constructed by use of a previously obtained synthetic gene and expressed in Escherichia coli under the...

Topics

Amino Acid Sequence
Animals
Circular Dichroism
DNA Glycosylases
Deoxyribonuclease (Pyrimidine Dimer)
Endodeoxyribonucleases
Escherichia coli
Genes, Regulator
In Vitro Techniques
Kinetics
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Mutation
N-Glycosyl Hydrolases
Plasmids
Terminator Regions, Genetic
Ultraviolet Rays

Source

Open in PubMed

Identifiers

PMID: 2191719
DOI: 10.1021/bi00468a002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2191719-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics