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Article

Multiple-site mutations of phage Bp7 endolysin improves its activities against target bacteria.

Virologica Sinica - 1 Oct 2015

Zhang Can, Wang Yuanchao, Sun Huzhi, Ren Huiying

Abstract excerpt

The widespread use of antibiotics has caused serious drug resistance. Bacteria that were once easily treatable are now extremely difficult to treat. Endolysin can be used as an alternative to antibiotics for the treatment of drug-resistant bacteria. To analyze the antibacterial activity of the endolysin of phage Bp7 (Bp7e), a 489-bp DNA fragment of endolysin Bp7e was PCR-amplified from a phage Bp7 genome and...

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Identifiers

PMID: 26490045
DOI: 10.1007/s12250-015-3618-z
PMCID: PMC8200918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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