Article
Limited frequency of the CYP2C19*17 allele and its minor role in a Japanese population.
British journal of clinical pharmacology - 1 Mar 2008
Sugimoto Katsuyoshi, Uno Tsukasa, Yamazaki Hiroshi, Tateishi Tomonori
Abstract excerpt
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: A novel CYP2C19 gene variant, CYP2C19*17, is associated with increased metabolic activity. Ethnic differences in the frequency of the variant allele have been reported. However, the frequency of the CYP2C19*17 allele has not been studied in the Japanese population. WHAT THIS STUDY ADDS: In a population of 265 healthy Japanese subjects, a low frequency (1.3%) of the...
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