Article
An erythropoietin gene polymorphism in the hypoxia-responsive element at position 3434 is possibly associated with hypertension.
Kidney & blood pressure research - 1 Jan 2012
Schulz E G, Neumann C L, Menne J, Schettler V, Mackenbrock C, Popov A F, Hagenah G C, Hinz J, Bargfeldt M, Gasser T, Haller H, Hermann M
Abstract excerpt
BACKGROUND/AIMS: Several polymorphisms of vasoactive hormones have been implicated in hypertension. Erythropoietin (EPO) interacts with vasoactive substances, such as angiotensin II. Previously detected single nucleotide polymorphisms in the hypoxia-responsive element of EPO might be associated with hypertension and hypertensive end organ damages. METHODS: 400 hypertensive patients and 200 age- and gender-matched...
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