Article
DMBT1 expression and glycosylation during the adenoma-carcinoma sequence in colorectal cancer.
Biochemical Society transactions - 1 Aug 2005
Robbe C, Paraskeva C, Mollenhauer J, Michalski J C, Sergi C, Corfield A
Abstract excerpt
The gene DMBT1 (deleted in malignant brain tumour-1) has been proposed to play a role in brain and epithelial cancer, but shows unusual features for a classical tumour-suppressor gene. On the one hand, DMBT1 has been linked to mucosal protection, whereas, on the other, it potentially plays a role in epithelial differentiation. Thus its function in a particular tissue is of mechanistic importance for its role in...
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