Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of MMP-9 in the anti-angiogenic effect of secreted protein acidic and rich in cysteine

19 Jan 2010

Abstract excerpt

BACKGROUND: Secreted protein acidic and rich in cysteine (SPARC), a matricellular glycoprotein, modulates cellular interaction with the extracellular matrix and is capable of altering the growth of various cancers. We therefore sought to determine the effect of SPARC expression on medulloblastoma tumour growth and angiogenesis. METHODS: To this extent, we selected three SPARC full-length cDNA overexpressed clones...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Dental Protein Studies
Share to Infant Nutrition and Health
Share to Protease and Inhibitor Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20087345
DOI: 10.1038/sj.bjc.6605538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of MMP-9 in the anti-angiogenic effect of secreted protein acidic and rich in cysteinePMID 20087345Read ↗

A prototypic matricellular protein in the tumor microenvironment—Where there's SPARC, there's fireSemantic proximity Read ↗

Molecular mechanisms underlying the divergent roles of SPARC in human carcinogenesisSemantic proximity Read ↗

The Expression of the Secreted Protein Acidic and Rich in Cysteine (SPARC) Is Associated with the Neoplastic Progression of Human MelanomaSemantic proximity Read ↗

Integrative genomic analyses of secreted protein acidic and rich in cysteine and its role in cancer prediction.Semantic proximity Read ↗

Secreted Protein Acidic and Rich in Cysteine (SPARC) Enhances Cell Proliferation, Migration, and Epithelial Mesenchymal Transition, and SPARC Expression is Associated with Tumor Grade in Head and Neck Cancer.Semantic proximity Read ↗

SPARC Represses E-Cadherin and Induces Mesenchymal Transition during Melanoma DevelopmentSemantic proximity Read ↗

SPARC: a matricellular regulator of tumorigenesisSemantic proximity Read ↗

Inhibition of endogenous SPARC enhances pancreatic cancer cell growth: modulation by FGFR1-III isoform expression.Semantic proximity Read ↗

SPARC, a matricellular protein that protects cancer from therapySemantic proximity Read ↗

HSP27 mediates SPARC‐induced changes in glioma morphology, migration, and invasionSemantic proximity Read ↗

ANALYSIS OF THE GENE EXPRESSION OF SPARC AND ITS PROGNOSTIC VALUE FOR BLADDER CANCERSemantic proximity Read ↗

Clinical significance of SPARC gene expression in patients with gastric cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.