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Article

Functions of EpCAM in physiological processes and diseases (Review)

11 Jul 2018

Abstract excerpt

EpCAM (epithelial cell adhesion molecule) is a type I transmembrane glycoprotein, which was originally identified as a tumor‑associated antigen due to its high expression level in rapidly growing epithelial tumors. Germ line mutations of the human EpCAM gene have been indicated as the cause of congenital tufting enteropathy. Previous studies based on cell models have revealed that EpCAM contributes to various...

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Identifiers

PMID: 30015855
DOI: 10.3892/ijmm.2018.3764

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