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Article

A molecular mousetrap determines polarity of termination of DNA replication in E. coli.

Cell - 30 Jun 2006

Mulcair Mark D, Schaeffer Patrick M, Oakley Aaron J, Cross Hannah F, Neylon Cameron, Hill Thomas M, Dixon Nicholas E

Abstract excerpt

During chromosome synthesis in Escherichia coli, replication forks are blocked by Tus bound Ter sites on approach from one direction but not the other. To study the basis of this polarity, we measured the rates of dissociation of Tus from forked TerB oligonucleotides, such as would be produced by the replicative DnaB helicase at both the fork-blocking (nonpermissive) and permissive ends of the Ter site. Strand...

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Identifiers

PMID: 16814717
DOI: 10.1016/j.cell.2006.04.040

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A molecular mousetrap determines polarity of termination of DNA replication in E. coli.PMID 16814717Read ↗

Strand separation establishes a sustained lock at the Tus-Ter replication fork barrier.Semantic proximity Read ↗

Differential Tus-Ter binding and lock formation: implications for DNA replication termination in Escherichia coli.Semantic proximity Read ↗

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Chromosomal directionality of DNA mismatch repair in Escherichia coli.Semantic proximity Read ↗

Tus-mediated arrest of DNA replication in Escherichia coli is modulated by DNA supercoiling.Semantic proximity Read ↗

Mutational bias suggests that replication termination occurs near the dif site, not at Ter sites.Semantic proximity Read ↗

Mutational bias suggests that replication termination occurs near the dif site, not at Ter sites: what's the Dif?Semantic proximity Read ↗

The Escherichia coli UvrD helicase is essential for Tus removal during recombination-dependent replication restart from Ter sites.Semantic proximity Read ↗

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