Article
The site-specific recombination system regulating expression of the type 1 fimbrial subunit gene of Escherichia coli is sensitive to changes in DNA supercoiling.
Molecular microbiology - 1 Dec 1994
Dove S L, Dorman C J
Abstract excerpt
We have studied the effect of altering the in vivo level of DNA supercoiling on the phase-variable expression of the Escherichia coli fimA gene. Transcription from the fimA promoter was unaffected by changes in DNA supercoiling whether caused by the introduction of a topA::Tn10 mutation or by inh...
Topics
- Bacterial Proteins
- Base Sequence
- DNA Probes
- DNA Topoisomerases, Type I
- DNA Transposable Elements
- DNA, Bacterial
- DNA, Superhelical
- Escherichia coli
- Fimbriae Proteins
- Fimbriae, Bacterial
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Molecular Sequence Data
- Mutation
- Novobiocin
- Nucleic Acid Conformation
- Promoter Regions, Genetic
- Recombination, Genetic