Article
Peroxisome proliferator-activated receptor pathway gene polymorphism associated with extent of coronary artery disease in patients with type 2 diabetes in the bypass angioplasty revascularization investigation 2 diabetes trial.
Circulation - 27 Sept 2011
Cresci Sharon, Wu Jun, Province Michael A, Spertus John A, Steffes Michael, McGill Janet B, Alderman Edwin L, Brooks Maria Mori, Kelsey Sheryl F, Frye Robert L, Bach Richard G
Abstract excerpt
BACKGROUND: Coronary artery disease (CAD) is the major cause of death in patients with type 2 diabetes mellitus. Although demographic and clinical factors associated with extent of CAD in patients with diabetes mellitus have been described, genetic factors have not. We hypothesized that genetic variation in peroxisome proliferator-activated receptor (PPAR) pathway genes, important in diabetes mellitus and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.