Article
PPARgamma gene C161T substitution alters lipid profile in Chinese patients with coronary artery disease and type 2 diabetes mellitus.
Cardiovascular diabetology - 24 Mar 2010
Wan Jing, Xiong Shixi, Chao Shengping, Xiao Jianming, Ma Yexin, Wang Jinghua, Roy Sabita
Abstract excerpt
BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPARgamma) is a ligand-activated transcription factor, which regulates gene expression of the key proteins involved in lipid metabolism, vascular inflammation, and proliferation. PPARgamma may contribute to attenuating atherogenesis and postangioplasty restenosis. PPARgamma C161-->T substitution is associated with a reduced risk of coronary artery...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
