Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toll-like receptor 4 rs11536889 is associated with angiographic extent and severity of coronary artery disease in a Chinese population.

Oncotarget - 10 Jan 2017

Sun Dandan, Wu Yupeng, Wang Honghu, Yan Hong, Liu Wen, Yang Jun

Abstract excerpt

Toll-like receptor 4 (TLR4) is a key modulator in many inflammation-related diseases. Polymorphisms in the TLR4 gene may alter TLR4 expression and affect the extent and severity of coronary artery disease (CAD). We analyzed 3 polymorphisms of TLR4 in 607 Chinese subjects who underwent coronary arteriography. Blood samples were collected to identify the polymorphisms. We evaluated the relationships between the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Angiography

Share to Coronary Artery Disease

Share to Genetic Association Studies

Share to Severity of Illness Index

Share to Toll-Like Receptor 4

Source

Open in PubMed Open full text

Identifiers

PMID: 28002812
DOI: 10.18632/oncotarget.14014
PMCID: PMC5356775

Genes

TLR4
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toll-like receptor 4 rs11536889 is associated with angiographic extent and severity of coronary artery disease in a Chinese population.PMID 28002812Read ↗

Coronary Artery Disease: Association Study of 5 Loci with Angiographic Indices of Disease Severity.Semantic proximity Read ↗

Vascular endothelial growth factor polymorphisms and extent of coronary atherosclerosis in Chinese population with advanced coronary artery disease.Semantic proximity Read ↗

CXCL5 is associated with the increased risk of coronary artery disease.Semantic proximity Read ↗

Promoter Polymorphism of Toll-Like Receptor 4 is Associated with a Decreased Risk of Coronary Artery Disease: A Case-Control Study in the Chinese Han Population.Semantic proximity Read ↗

Association of C5aR1genetic polymorphisms with coronary artery disease in a Han population in Xinjiang, China.Semantic proximity Read ↗

MIF Gene Polymorphism rs755622 Is Associated With Coronary Artery Disease and Severity of Coronary Lesions in a Chinese Kazakh Population: A Case-Control Study.Semantic proximity Read ↗

Association of polymorphisms at LDLR locus with coronary artery disease independently from lipid profile.Semantic proximity Read ↗

The effect of genetic polymorphisms of TLR2 and TLR4 in Turkish patients with coronary artery disease.Semantic proximity Read ↗

Peroxisome proliferator-activated receptor pathway gene polymorphism associated with extent of coronary artery disease in patients with type 2 diabetes in the bypass angioplasty revascularization investigation 2 diabetes trial.Semantic proximity Read ↗

Association of Toll-Like Receptor 4 Gene Polymorphisms with Acute Aortic Dissection in a Chinese Han Population.Semantic proximity Read ↗

[Association between single nucleotide polymorphisms of matrix metalloproteinase-3 gene and the severity of coronary atherosclerosis in patients with coronary artery disease].Semantic proximity Read ↗

Genetic Analysis Reveals Different Mechanisms of IL-5 Involved in the Development of CAD in a Chinese Han Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.