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Article

Association of combined genetic variations in PPARγ, PGC-1α, and LXRα with coronary artery disease and severity in Thai population.

Atherosclerosis - 1 May 2016

Yongsakulchai Pratthana, Settasatian Chatri, Settasatian Nongnuch, Komanasin Nantarat, Kukongwiriyapan Upa, Cote Michele L, Intharapetch Pongsak, Senthong Vichai

Abstract excerpt

BACKGROUND: Atherosclerosis is a major cause of coronary artery disease (CAD). Peroxisome proliferator-activated receptor-γ (PPARγ), liver X receptor-α (LXRα), and PPARγ co-activator-1α (PGC-1α) are nuclear factors that regulate lipid metabolism and inflammation implicated in atherosclerosis. Although association of genetic variations in these nuclear factors with CAD risk has been reported, it was based on...

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Source

Identifiers

PMID: 27016616
DOI: 10.1016/j.atherosclerosis.2016.03.005

Genes

CAD
PGC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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