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New insights into the role of centrosomes in mammalian fertilization and implications for ART

13 Sept 2011

Abstract excerpt

In non-rodent mammalian species, including humans, the oocyte and sperm both contribute centrosomal components that are most important for successful fertilization. Centrosome pathologies in sperm and the oocyte can be causes for infertility which may be overcome by assisted reproductive technologies based on proper diagnosis of specific centrosomal pathologies. However, we do not yet fully understand the cell...

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PMID: 21911443
DOI: 10.1530/rep-11-0261

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