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Sperm centriolar factors and genetic defects that can predict pregnancy

22 Jul 2023

Abstract excerpt

The human sperm centrosome, comprising the two morphologically distinct centrioles and associated pericentriolar materials, plays a crucial role in fertilization and early embryonic development after fertilization. Once inside the oocyte, the sperm centrosome serves as a microtubule-organizing center, orchestrating mitotic spindle formation, chromosome segregation, and syngamy. Abnormalities of the sperm...

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PMID: 37487819
DOI: 10.1016/j.fertnstert.2023.07.007

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