Article
Schizophrenia-related RGS4 gene variations specifically disrupt prefrontal control of saccadic eye movements.
Psychological medicine - 1 Apr 2012
Kattoulas E, Stefanis N C, Avramopoulos D, Stefanis C N, Evdokimidis I, Smyrnis N
Abstract excerpt
BACKGROUND: The gene encoding the regulator of G-protein signaling subtype 4 (RGS4), located on chromosome 1q23-3, has been proposed as a possible susceptibility gene for schizophrenia and has been specifically linked to prefrontal cortical structural and functional integrity. METHOD: The effects of four core single nucleotide polymorphisms (SNPs) within the RGS4 gene on oculomotor parameters in a battery of...
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