Article
Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study.
Translational psychiatry - 24 Oct 2017
Lencer R, Mills L J, Alliey-Rodriguez N, Shafee R, Lee A M, Reilly J L, Sprenger A, McDowell J E, McCarroll S A, Keshavan M S, Pearlson G D, Tamminga C A, Clementz B A, Gershon E S, Sweeney J A, Bishop J R
Abstract excerpt
Eye movement deviations, particularly deficits of initial sensorimotor processing and sustained pursuit maintenance, and antisaccade inhibition errors, are established intermediate phenotypes for psychotic disorders. We here studied eye movement measures of 849 participants from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study (schizophrenia N=230, schizoaffective disorder N=155,...
Topics
- Adult
- Bipolar Disorder
- Female
- Genome-Wide Association Study
- Genotype
- Humans
- Male
- Phenotype
- Polymorphism, Single Nucleotide
- Psychotic Disorders