Article
Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples.
Biological psychiatry - 15 Jul 2006
Talkowski Michael E, Seltman Howard, Bassett Anne S, Brzustowicz Linda M, Chen Xiangning, Chowdari Kodavali V, Collier David A, Cordeiro Quirino, Corvin Aiden P, Deshpande Smita N, Egan Michael F, Gill Michael, Kendler Kenneth S, Kirov George, Heston Leonard L, Levitt Pat, Lewis David A, Li Tao, Mirnics Karoly, Morris Derek W, Norton Nadine, O'Donovan Michael C, Owen Michael J, Richard Christian, Semwal Prachi, Sobell Janet L, St Clair David, Straub Richard E, Thelma B K, Vallada Homero, Weinberger Daniel R, Williams Nigel M, Wood Joel, Zhang Feng, Devlin Bernie, Nimgaonkar Vishwajit L
Abstract excerpt
BACKGROUND: Associations between schizophrenia (SCZ) and polymorphisms at the regulator of G-protein signaling 4 (RGS4) gene have been reported (single nucleotide polymorphisms [SNPs] 1, 4, 7, and 18). Yet, similar to other SCZ candidate genes, studies have been inconsistent with respect to the associated alleles. METHODS: In an effort to resolve the role for RGS4 in SCZ susceptibility, we undertook a...
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