Article
Schizophrenia-related neuregulin-1 single-nucleotide polymorphisms lead to deficient smooth eye pursuit in a large sample of young men.
Schizophrenia bulletin - 1 Jul 2011
Smyrnis Nikolaos, Kattoulas Emmanouil, Stefanis Nicholas C, Avramopoulos Dimitrios, Stefanis Costas N, Evdokimidis Ioannis
Abstract excerpt
Neuregulin-1 (NRG1) variations have been shown to modulate schizophrenia candidate endophenotypes related to brain structure and function. The aim of this study was to determine the effect of NRG1 on several oculomotor schizophrenia endophenotypes. The effects of 5 core single-nucleotide polymorphisms (SNPs) within the NRG1 gene to oculomotor parameters in a battery of oculomotor tasks (saccade, antisaccade,...
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