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Article

Association of chronic inflammation and accelerated atherosclerosis among an indigenous black population with chronic kidney disease.

PloS one - 1 Jan 2020

Hassan Muzamil Olamide, Dix-Peek Therese, Duarte Raquel, Dickens Caroline, Naidoo Sagren, Vachiat Ahmed, Grinter Sacha, Manga Pravin, Naicker Saraladevi

Abstract excerpt

INTRODUCTION: Inflammation plays a major role in the development of atherosclerosis and cardiovascular morbidity and mortality in chronic kidney disease (CKD) patients. Toll-like receptor-4 (TLR4) is a major receptor for lipopolysaccharides (endotoxin) and other ligands involved in the pathogenesis of inflammation. We determined whether endotoxin levels and the presence of TLR4 polymorphisms are associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32649699
DOI: 10.1371/journal.pone.0232741
PMCID: PMC7351182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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