Article
Analysis of a soluble mutant des-methionine interleukin-2 receptor alpha chain (Tac protein) produced by transfected mammalian cells.
European journal of biochemistry - 20 May 1990
Beckers T, Hauser H, Hüsken D, Engels J W
Abstract excerpt
By using recombinant DNA technology the cytoplasmic and trans-membrane domain of the human interleukin-2 receptor alpha chain (IL-2R alpha, Tac) and of a mutant protein lacking methionine-residues 18, 25, 44, 88, 92, 126, 149, 167, 205, and 209 (des-Met IL-2R alpha) encoded by a chemically and en...
Topics
- Base Sequence
- Cell Line
- Chromosome Deletion
- DNA
- Enzyme-Linked Immunosorbent Assay
- Humans
- In Vitro Techniques
- Membrane Proteins
- Methionine
- Molecular Probe Techniques
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Plasmids
- Protein Engineering
- Protein Processing, Post-Translational
- Receptors, Interleukin-2
- Transfection