Article
Immobilization and internalization of mutated IgE receptors in transfected cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1991
Mao S Y, Varin-Blank N, Edidin M, Metzger H
Abstract excerpt
Earlier studies have shown that the mast cell receptor IgE (Fc epsilon RI) for is expressed on COS-7 cells transfected with the cDNA for each of the three types of subunits that form the tetrameric, alpha beta gamma 2, receptor. Although such transfected COS cells fail to exhibit some of the early biochemical perturbations initiated by aggregation of the receptor on normal mast cells and related tumor lines, we...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Differentiation, B-Lymphocyte
- Cytochalasin D
- Diffusion
- Dinitrophenols
- Endocytosis
- Mice
- Molecular Sequence Data
- Mutation
- Receptors, Fc