Article
Variations in the STK10 gene and possible associations with aspirin-intolerant asthma in a Korean population.
Journal of investigational allergology & clinical immunology - 1 Jan 2011
Kim J H, Park B L, Cheong H S, Pasaje C F A, Bae J S, Park J S, Jang A S, Uh S T, Choi J S, Kim Y H, Kim M K, Choi I S, Cho S H, Choi B W, Koh I S, Park C S, Shin H D
Abstract excerpt
BACKGROUND AND OBJECTIVE: Lymphocyte-oriented kinase deficiency encoded by the serine/threonine kinase 10 (STK10) gene correlates with the intracellular adhesion molecule 1 (ICAM-1)/lymphocyte function associated antigen 1 (LFA-1) complex in aspirin hypersensitivity. This study investigated the association between single nucleotide polymorphisms (SNPs) of STK10 and aspirin-intolerant asthma (AIA). METHODS: A...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.