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Article

Genetic variation in liver X receptor alpha and risk of ischemic vascular disease in the general population.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2011

Stender Stefan, Frikke-Schmidt Ruth, Anestis Aristomenis, Kardassis Dimitris, Sethi Amar A, Nordestgaard Børge G, Tybjærg-Hansen Anne

Abstract excerpt

OBJECTIVE: Although animal studies indicate that liver X receptor alpha (LXRα) might influence risk of atherosclerosis, data in humans remain scarce. We tested the hypothesis that genetic variation in LXRα associates with risk of ischemic vascular disease and/or plasma lipid and lipoprotein levels in the general population. METHODS AND RESULTS: We studied 10,281 white persons of Danish ancestry from a general...

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Identifiers

PMID: 21903943
DOI: 10.1161/ATVBAHA.111.223867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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