Article
Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease.
The Journal of clinical endocrinology and metabolism - 1 Apr 2009
Johannsen Trine Holm, Kamstrup Pia R, Andersen Rolf V, Jensen Gorm B, Sillesen Henrik, Tybjaerg-Hansen Anne, Nordestgaard Børge G
Abstract excerpt
CONTEXT: Hepatic lipase influences metabolism of high-density lipoprotein (HDL), a risk factor for ischemic cardiovascular disease (ICD: ischemic heart disease and ischemic cerebrovascular disease). OBJECTIVE: We tested the hypothesis that genetic variation in the hepatic lipase genetic variants V73M, N193S, S267F, L334F, T383M, and -480c>t influence levels of lipids, lipoproteins, and apolipoproteins and risk of...
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