Article
Association between the rs2279238 of the Liver X receptor alpha gene polymorphism and advanced carotid atherosclerosis in the Slovenian cohort.
Gene - 5 Oct 2022
Grbić Emin, Gorkič Nataša, Pleskovič Aleš, Ljuca Farid, Gasparini Mladen, Mrđa Božidar, Cilenšek Ines, Fras Zlatko, Petrovič Daniel
Abstract excerpt
BACKGROUND: Liver X receptor alpha (LXRA) plays important role in cholesterol and lipid homeostasis and lipid metabolism; moreover, it has been investigated as a candidate gene in a number of conditions, including onset and progression of atherosclerosis. We hypothesized that the LXRA gene rs2279238 polymorphism may be associated with the onset and progression of carotid atherosclerosis in the Slovenian cohort....
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