Article
Associations between liver X receptor polymorphisms and blood lipids: A systematic review and meta-analysis.
Steroids - 1 Sept 2022
Zhang Huifeng, Lianto Priscilia, Li Weiming, Xu Mengfan, Moore J Bernadette, Thorne James L
Abstract excerpt
Genetic susceptibility to dyslipidaemia remains incompletely understood. The liver X receptors (LXRs), members of the nuclear receptor superfamily of ligand dependent transcription factors, are homeostatic regulators of lipid metabolism. Multiple single nucleotide polymorphisms (SNPs)have been identified previously in the coding and regulatory regions of the LXRs. The aim of this systematic review and...
Topics
- Lipids
- Lipoproteins
- Liver X Receptors
- Orphan Nuclear Receptors
- Polymorphism, Single Nucleotide
- Triglycerides
