Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Roles of NADPH Oxidase-Mediated Oxidative Stress in Alzheimer’s Disease: Isoform-Specific Contributions

15 Nov 2024

Abstract excerpt

Oxidative stress is linked to the pathogenesis of Alzheimer's disease (AD), a neurodegenerative disorder marked by memory impairment and cognitive decline. AD is characterized by the accumulation of amyloid-beta (Aβ) plaques and the formation of neurofibrillary tangles (NFTs) of hyperphosphorylated tau. AD is associated with an imbalance in redox states and excessive reactive oxygen species (ROS). Recent studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Neurological disorders and treatments
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39596364
DOI: 10.3390/ijms252212299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Roles of NADPH Oxidase-Mediated Oxidative Stress in Alzheimer’s Disease: Isoform-Specific ContributionsPMID 39596364Read ↗

Neuronal NOX4 knockdown alleviates pathological tau-related alterations in a humanized mouse model of tauopathySemantic proximity Read ↗

Implication of type 4 NADPH oxidase (NOX4) in tauopathySemantic proximity Read ↗

Oxidative stress mediates the pathogenic effect of different Alzheimer’s disease risk factorsSemantic proximity Read ↗

Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s Disease: Insights into Pathophysiology and TreatmentSemantic proximity Read ↗

Insights into targeted ferroptosis in mechanisms, biology, and role of Alzheimer's disease: an updateSemantic proximity Read ↗

miR-204-3p/Nox4 Mediates Memory Deficits in a Mouse Model of Alzheimer’s DiseaseSemantic proximity Read ↗

Is oxidative damage central to the pathogenesis of Alzheimer disease?Semantic proximity Read ↗

Ferroptosis as a mechanism of neurodegeneration in Alzheimer's diseaseSemantic proximity Read ↗

NOX4-mediated astrocyte ferroptosis in Alzheimer’s diseaseSemantic proximity Read ↗

Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer’s DiseaseSemantic proximity Read ↗

The 5-lipoxygenase pathway: oxidative and inflammatory contributions to the Alzheimerâ€™s disease phenotypeSemantic proximity Read ↗

A Concise Review on Oxidative Stress-Mediated Ferroptosis and Cuproptosis in Alzheimer’s DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.