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Article

Stretch-activated calcium channel protein TRPC1 is correlated with the different degrees of the dystrophic phenotype in mdx mice.

American journal of physiology. Cell physiology - 1 Dec 2011

Matsumura Cíntia Yuri, Taniguti Ana Paula Tiemi, Pertille Adriana, Santo Neto Humberto, Marques Maria Julia

Abstract excerpt

In Duchenne muscular dystrophy (DMD) and in the mdx mouse model of DMD, the lack of dystrophin is related to enhanced calcium influx and muscle degeneration. Stretch-activated channels (SACs) might be directly involved in the pathology of DMD, and transient receptor potential cation channels have been proposed as likely candidates of SACs. We investigated the levels of transient receptor potential canonical...

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Source

Identifiers

PMID: 21900691
DOI: 10.1152/ajpcell.00056.2011

Genes

TRPC1
DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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