Article
Calcium-binding proteins in skeletal muscles of the mdx mice: potential role in the pathogenesis of Duchenne muscular dystrophy.
International journal of experimental pathology - 1 Feb 2010
Pertille Adriana, de Carvalho Candida Luiza Tonizza, Matsumura Cintia Yuri, Neto Humberto Santo, Marques Maria Julia
Abstract excerpt
Duchenne muscular dystrophy is one of the most common hereditary diseases. Abnormal ion handling renders dystrophic muscle fibers more susceptible to necrosis and a rise in intracellular calcium is an important initiating event in dystrophic muscle pathogenesis. In the mdx mice, muscles are affec...
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