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Article

WT1-interacting protein (Wtip) regulates podocyte phenotype by cell-cell and cell-matrix contact reorganization.

American journal of physiology. Renal physiology - 1 Jan 2012

Kim Jane H, Mukherjee Amitava, Madhavan Sethu M, Konieczkowski Martha, Sedor John R

Abstract excerpt

Podocytes respond to environmental cues by remodeling their slit diaphragms and cell-matrix adhesive junctions. Wt1-interacting protein (Wtip), an Ajuba family LIM domain scaffold protein expressed in the podocyte, coordinates cell adhesion changes and transcriptional responses to regulate podocyte phenotypic plasticity. We evaluated effects of Wtip on podocyte cell-cell and cell-matrix contact organization using...

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Identifiers

PMID: 21900451
DOI: 10.1152/ajprenal.00419.2011
PMCID: PMC3251346

Genes

WTIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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WT1-interacting protein (Wtip) regulates podocyte phenotype by cell-cell and cell-matrix contact reorganization.PMID 21900451Read ↗

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